glutathione depletion methylation cycle block induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells Methylation deficiency disrupts biological rhythms
Description
AKB-6548, a new hypoxia-inducible factor prolyl hydroxylase inhibitor increases hemoglobin while decreasing ferritin in a 28-day, phase 2a dose escalation study in stage 3 and 4 chronic kidney disease patients with anemia [abstract]
Additional file 1: Table S4)
Matchar DB, McCrory DC, Millington DS, Feuss- ner JR
In Vitro 51 , 1122 (2018)
