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About This Issue Although thyroid disorders are common, decompensated hypothyroidism and thyroid storm represent the rare, life-threatening, extreme ends of the spectrum of thyroid dysfunction

However, under pathological conditions, excessively activated NSPs become major drivers of tissue destruction, contributing to the development and progression of various inflammatory lung diseases ( The three primary NSPs exhibit both shared and distinct functional characteristics

GSH-Px, thioredoxin reductase and the thyroid hormone deiodinase are involved in intracellular signaling, redox homeostasis and thyroid hormone metabolism regulation (15)

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