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In later stages, the bladder may become completely obstructed and the patient may not be able to urinate at all

Biofilms were visualised by Confocal Laser Scanning Microscopy (CSLM) (Olympus FV1200, Australia) with Ex/Em 473/559 nm and Ex/Em 500/637 nm for Syto 9 (green for live cells) and PI (red for damaged and dead cells) staining, respectively

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- In the case of any local internal leg pain, interrupt the administration, withdraw the needle and apply elsewhere in the area
