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The atypical enzymatic activity of nuclear LDHA catalyzes the conversion of -KB to - hydroxybutyrate (-HB), leading to -HB accumulation

With the rapid development of high-throughput sequencing technology, genomics has gradually transitioned from basic research to clinical applications, providing strong technical support for the precise diagnosis and targeted treatment of cancer (Mukherjee, 2019)

Cedillo-Flores et al., 2025)

Acute brain damagetrauma and ischemia Acute trauma, ischemia and stroke are characterized by prominent increases in the presence and activity of Cx43 hemichannels in astrocytes, contributing to the secondary damage of the nervous tissue 478
