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Linearity and sensitivity Figure 3 illustrates that the new GPx-Tiron assay exhibits excellent analytical performance across a broad range of enzymatic activities

For example, intranasal administration of edaravone PLGA nanoparticles showed improved brain stability and bioavailability and reduced H 2 O 2 -induced oxidative stress toxicity in mouse microglial cell line BV-2 (Lu et al., 2023)

Upregulation of CHAC1 has been consistently observed in models of retinal damage, kidney and liver injury and heat shockinduced oxidative stress, often in tandem with ER stress ( In acetaminophen (APAP)-induced liver injury, CHAC1 indirectly promotes ferroptosis by modulating the ferroptosis suppressor ARF6