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Vitamin B12 supplementation is a very safe treatment, but should only be administered with veterinary supervision to ensure correct dosage and duration of treatment

The sequences of specific primers used for RT-qPCR in this study are listed in Supplementary Table S1

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During erythropoiesis, amino acid metabolism (e.g., glycine, glutamine, branched-chain amino acids) is essential to heme synthesis as both direct and indirect substrates (e.g., succinyl-CoA from glutaminolysis and branched-chain amino acid catabolism)
