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doi: 10.1179/1351000211Y.0000000012

Preclinical data suggest AHK-Cu may stimulate collagen and elastin production in dermal fibroblast models, with associated increases in dermal matrix density in animal studies, proposed to occur through AHK-Cu's modulation of VEGF and TGF-1 expression activating both fibroblasts (which build structural matrix proteins) and endothelial cells (which support the vascular network needed for tissue regeneration).[4] A separate in vitro study by Pyo et al

Dihexa acetate can be developed as a single-ingredient formulation or combined with other nootropic active ingredients for pharmacological intervention in the later stages of nerve damage repair and age-related cognitive decline
In a study of very-low-birth-weight infants, Chabra et al
