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Metabolic symbiosis: nutrient exchange supporting CSCs CSCs establish metabolic symbiosis with surrounding stromal cells to ensure a continuous supply of energy substrates for survival and proliferation 311 (Fig

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Elevated expression of the HKDC1 gene is found in numerous types of cancer and this is associated with poor prognosis such as is the case for hepatocellular carcinoma and squamous cell lung carcinoma (SQCLC)

Presumably, other types of TmGst could play a role in detoxifying other xenobiotics, including antifungal drugs