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It is being successfully used in breast cancer[ref], leukemia[ref], non-small cell lung cancer[ref], colon cancer[ref][ref], head and neck cancer[ref], and more.[ref] Melatonin also suppresses the Warburg effect, which is how cancer cells fuel their growth

HUBERMAN: For instance, activating one pathway for cellular growth and another pathway for cell migration, for the cell to actually move, and maybe another pathway to talk to another cell to stimulate, say, the growth of blood vessels

Among these genes, the Methylenetetrahydrofolate Reductase (MTHFR) holds a significant role, especially when mutated

doi: 10.1007/s11157-016-9390-1 44 HafeezB.KhanifY.SaleemM