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Description
Optical reporters have a light-based readout that can be fluorescent (e.g., GFP 650652 ), colorimetric (e.g., -galactosidase (lacZ) 249,653,654 ), or luminescent (e.g., luciferase 637 )

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In untrained individuals, the cerebral circulation exhibits greater sensitivity to reductions (than increases) in mean arterial pressure, demonstrating a greater change in MCAv (and assumingly CBF) during a hypotensive stimulus compared to a hypertensive stimulus (Roy et al., 2022

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