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However, when exposed to the same concentrations of Fe 3+ , the survival rate of the deletion strain was significantly higher than that of the parental strain (Figure 2B), while no viable bacteria were detected in all strains at the same concentrations of Cu 2+ , so the concentrations of Cu 2+ were reduced to 5 mM

Emerging evidence has indicated that p53-KR interrupts the import of cystine, and ultimately results in GSH depletion and cell death in a ferroptotic manner [16]

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