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Potential Risks of Dental Amalgam: Contains elemental mercury
While not everyone with IgG4-RD experiences headaches, the disease can impact areas that lead to persistent or severe headaches, such as: The meninges: These protective brain layers can thicken and become inflamed (hypertrophic pachymeningitis), resulting in ongoing, sometimes debilitating headaches

Amyotrophic lateral sclerosis (ALS) is another neurodegenerative disease where oxidative stress plays a central role
doi: 10.1095/biolreprod.110.086744 154