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The largest natural pulse of growth hormone we experience occurs during the first few hours of deep, slow-wave sleep
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doi: 10.18632/aging.203319
During the S phase, ROS activate the ATR/Chk1 signaling pathway 90 , inhibit CDC25A 91 and PCNA activity 92 , and block progression to the G2 phase through the involvement of ATM 93 and MTH1 92
