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Patient characteristics associated with severe hypoglycemia in a type 2 diabetes cohort in a large, integrated health care system from 2006 to 2015

In brief: mutant, wild type and complemented strains were inoculated into 5 mL of YEPD and incubated with orbital agitation 150 rpm for 1618 h

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 2% by weight of the povidone

This contributes to the scientific hypothesis that administration of MOTS-c may contribute mitochondrial homeostasis, and impart an anti-aging effect on those treated