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Description
IMP, inner membrane protein
The mLOC is composed of the monocarboxylate transporters, MCT1 and MCT4 (and possibly MCT2), the lactate dehydrogenase isoforms, LDHA and LDHB, cytochrome oxidase (complex IV of oxidative phosphorylation), and a scaffolding chaperone basignin (previously identified as CD147)
This spectrum of hepatic disorders can progress to severe conditions, such as non-alcoholic steatohepatitis (NASH) and cirrhosis, due to oxidative stress and sustained cellular injury
10.2147/DDDT.S270124 172 SongL.WangH
