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To identify potential outliers, principal component analysis was performed after log transformation and Pareto scaling were applied to the entire dataset using MetaboAnalyst 5.0 online software ( Two control samples were identified as outliers and removed from the dataset before further statistical analyses were performed

9 Materials and methods A structured literature review (PRISMA 2020) was conducted across PubMed, Embase, Cochrane Library, Scopus, and Google Scholar to 31 January 2026

CaMKII induces permeability transition through Drp1 phosphorylation during chronic -AR stimulation

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