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Tenofovir was excreted into the milk of lactating rhesus monkeys, following a single subcutaneous (30 mg/kg) dose of tenofovir, at concentrations up to approximately 4% of plasma concentration resulting in exposure (AUC) of approximately 20% of plasma exposure

[DOI] [PMC free article] [PubMed] [Google Scholar] Kysenius K, Muggalla P, Mtlik K, Arume U, Huttunen HJ, 2012

Pharmacological research : the official journal of the Italian Pharmacological Society

Instead, they influence energy balance through alternative pathways, including reduced caloric intake, improved insulin sensitivity, and altered fat storage mechanisms