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3.2.1.2 Solid lipid nanoparticles Solid lipid nanoparticles (SLN) are discs or elliptical spherical particles composed of solid lipids, water, and surfactants at room temperature, and the drug may be attached to the surface of the carrier or encapsulated in a core (Scioli Montoto et al., 2020)

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10.1016/j.bbrc.2020.03.094 352 SunY.MaC.SunH.WangH.PengW.ZhouZ.et al

[40], in which the inorganic phosphate released upon hydrolysis of GTP is coupled to a reaction catalysed by purine nucleoside phosphorylase (PNP) using methylthioguanosine (MESG) as substrate