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Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease

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2 2.8.3 Widely targeted metabolomics analysis Frozen tissue specimens were homogenized and extracted using ice-cold methanol:water (7:3, v/v) supplemented with isotope-labeled internal standards,followed by multi-platform LC-MS/MS analysis

This suggested that wound healing was nearly complete in the G/D-CuP group with minimal new blood vessel formation on day 12, whereas the M-CuP and G/M-CuP groups, still in the healing process, exhibited increased angiogenesis