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J Nutr 127:948S-950S

To increase the effective concentration of antioxidants, some trials used high doses of antioxidants, which in turn promote oxidation

These discrepancies may be attributed to variations in study design, sample size, and trial standards

9.3 Cardiomyocyte protective In the angiotensin II-exposed H9C2 cells, ISA can increase the expression of Nrf2 and HO-1, enhancing the antioxidant capacity of cells, which helps to resist the detrimental effects imposed by angiotensin II, such as oxidative stress and apoptosis induction
