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In hypertensive patients, certain gene loci frequently show abnormal DNA methylation [65, 66]
10.1016/j.tcb.2020.08.008 Trends Cell Biol

The implications cascade through multiple metabolic pathways

In addition, T2D is the result of a complex interaction of environmental and genetic factors, being difficult to establish the role of each one in the pathogenesis of diabetes and in the levels of IGF-1
