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The mitochondrion has a double-membraned structure, and various heteroplasmy levels in different tissues, which poses challenges in therapeutic design and effectiveness (Tyynismaa and Suomalainen, 2009)

J Nutr (2001) 131:846S50S

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Curcumin heals indomethacin-induced gastric ulceration by stimulation of angiogenesis and restitution of collagen fibers via VEGF and MMP-2 mediated signaling
