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Patients receiving b12 for pernicious anemia, neurological conditions, or documented deficiency do not report nausea improvement unless their nausea stemmed from the deficiency itself

Oral and parenteral magnesium supplements were relatively ineffective at correcting the problem, but stopping PPI therapy lead to prompt resolution of the hypomagnesemia (within 2 weeks in five carefully monitored patients), with symptomatic benefit

it exports fat and bile from the liver which is responsible for seeing exported fat and burning it for energy and fuel

Areas requiring further investigation include: Tissue-specific dose optimisation: While 10-20 g/kg appears broadly effective across various tissues, whether specific tissues (cartilage versus muscle versus nerve) respond optimally to different doses has not been systematically explored