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On the other hand, the bioavailability of B12 from dietary supplements is 50% more than that from food sources
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Certain factors may put you at increased risk for B12 deficiencyincluding a vegetarian or vegan diet, specific medical conditions (such as Crohns or celiac disease, or a history of gastric surgery), and age over 50

The stoichiometry of gbeta gamma binding to G-protein-regulated inwardly rectifying K+ channels (GIRKs)