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[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Martina J.A., Chen Y., Gucek M., Puertollano R

If this amount is exceeded in a single dose, absorption becomes dependent on passive and diffuse mechanisms, which are much less efficient

Biol Trace Elem Res Res

These changes are further intensified by acidic pH, divalent metal ions, and familial mutations (e.g., A53T and E46K), which disrupt droplet fluidity and enhance aggregation kinetics [177, 183]
