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Additionally, investigations have found that Nrf2 plays a protective effect in neurodegenerative disorders [101,102]

10.1016/j.arabjc.2021.103084 13 ChenL.DengH.CuiH.FangJ.ZuoZ.DengJ.et al (2018)

The canonical pyroptosis pathway is initiated by the activation of the NLRP3 inflammasome complex, which includes NLRP3, the adaptor protein ASC containing the CARD domain, and pro-caspase-1 [65]

PMID 16578412
