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The investigators reported that oral AOD-9604 administration in rodent models produced measurable increases in fat oxidation and reductions in body fat, and that direct application of the compound to ex vivo human adipose tissue produced concentration-dependent increases in lipolysis [2]

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Curcumin increases anti-oxidant protection by improving strength and physical performance in elderly subjects, potentially preventing the onset of sarcopenia and blocking the progression of proinflammatory signaling [164]