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The vitamin B12 test can be used for: Monitoring the health of pregnant women Checking the reason for low vitamin B12 deficiency Diagnosing pernicious anemia Determining any interference by any medicine in the absorption of vitamin B12 Evaluating the nutritional status, i.e., poor diet or malnutrition Monitoring the treatment of vitamin B12 deficiency Routine checkups to monitor your overall health If your doctor suspects having symptoms of low vitamin B12 such as weakness, fatigue, painful tongue due to inflammation or infection, or feeling of pins and needles in hands, he may suggest you take a vitamin B12 test to confirm the diagnosis