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*Correspondence: Li Wu [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Ensure proper site rotation (not injecting the same spot repeatedly), use alcohol swabs consistently, and inject at room temperature (taking the vial out 15 to 20 minutes before injection can help)

Vitamins that are Beneficial for Myalgic Encephalomyelitis High-dose B12 is a remedy I have found very useful