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The increased entry of calcium ions (Ca2+) into mitochondria can lead to ROS generation and depolarization of the mitochondrial membrane, all occurring without ATP synthesis (Susin et al., 1998

Ethics statement The animal study was reviewed and approved by the Committee of Laboratory Animal Experimentation at Southwest University

These include gastrointestinal bleeding, kidney impairment or allergic reaction

The results showed that polysaccharides extracted from Pleurotus ostreatus can scavenge DPPH and ABTS free radicals, absorb water and have an inhibitory effect on collagenase and elastase activity
