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Additionally, FP regulates intestinal epithelial NLRP6 inflammasome activity, promotes -defensin-2/3 secretion, and competitively inhibits colonization by pro-inflammatory microorganisms such as Candida albicans and Escherichia coli (88)

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10.1038/ncb1486 55

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Patients who skip the break period and run continuous cycles do not get proportionally better outcomes and risk diminishing returns on the therapeutic response

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