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Hu Y, Zhou Y, Yang Y et al (2022) Metformin protects against diabetes-induced cognitive dysfunction by inhibiting mitochondrial fission protein DRP1

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A lower dose may help maintain baseline antioxidant levels, while a higher dose is often needed when: Oxidative stress is high Skin dullness or uneven tone is more visible You want noticeable skin benefits Environmental exposure (pollution, sun) is high This is where the difference between 100 mg and 1000 mg becomes important

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Due to the limited regenerative capacity of cardiomyocytes, the cardiac ECM is gradually replaced by scar tissue as heart failure progresses following a MI

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Susanti D, Ruslan FS, Shukor MI, Nor NM, Aminudin NI, Taher M, Khotib J

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