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Although currently not FDA-approved as a medical treatment, ozone therapy demonstrates considerable therapeutic applications in the management of musculoskeletal disorders, including osteoarthritis and chronic pain syndromes

The nausea and appetite suppression it causes follow directly from the locations of those receptors (Wilding et al., NEJM 2021)

& Doring, G

[DOI] [PubMed] [Google Scholar] 22.Nakamura T, Onage T, Kitizawa T
