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Description

M.BlomquistT

Role of metabolic H 2 O 2 generation: redox signaling and oxidative stress

Peroxytrifluoroacetic acid oxidizes the existing nitroso moiety (Scheme 10a), while nitric acid effects the exchange of the nitroso and nitro groups (Scheme 10b)

Interestingly, in the context of ob/ob mice, -cell overexpression of GPx1 is beneficial, decreasing hyperglycemia and preserving -cell volume and the accumulation of insulin stores in granules [102]