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Physiological redox signaling operates within defined spatial and temporal limits, whereas sustained ROS overproduction overwhelms antioxidant buffering systems and causes lipid peroxidation, protein carbonylation, DNA damage, and neuronal dysfunction

In conditions like Long COVID and ME/CFS, the immune system often remains locked in a state of chronic, maladaptive activation long after the initial infectious trigger has passed

Incidence of thrombotic complications in critically ill ICU patients with COVID-19

Muscle cell death mainly occurs through apoptosis, necrosis, and autophagy, resulting in muscle fiber loss and promoting the progression of sarcopenia