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What makes this particularly exciting is that NAD+ supplementation activates something called sirtuins

Its substrate specificity is also very high because activity on other hexose phosphates (e.g., mannose 6-phosphate or galactose 6-phosphate) is negligible

Especially when the source of transplanted mitochondria is exogenous, whether mitochondria as an exogenous substance causes an immune response is something to think about and verify

And in some tissues, increased DHT might even be a response to increased inflammation
