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doi: 10.1007/s001250051551
[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Radeva-Ilieva M., Stoeva S., Hvarchanova N., Zhelev I., Georgiev K.D
Antioxidant Protection Increases endogenous antioxidant enzymes (e.g., superoxide dismutase)
In vitro and in vivo models, knockout or inhibition of GPX4 can rapidly induce severe lipid peroxidation, mitochondrial rupture, and typical ferroptosis phenotypes in chondrocytes, further reinforcing its core role in maintaining joint homeostasis (Sun S
