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Safety and tolerability of the hexadecapeptide AOD9604 in humans. J Endocrinol Metab 3(12):715

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Nanogels, as a type of hydrogel, retain their high degree of hydration and swelling properties [39], and with their three-dimensional cross-linked network structure, they can encapsulate drugs with different chemical structures and properties

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In addition, recent studies using liver-specific Zip14 KO mice displayed an almost complete loss of hepatic Mn, demonstrating that ZIP14 is the primary transporter responsible for Mn uptake into the liver (Xin et al., 2017

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Gutman AB, Yu TF, Berger L

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