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In mice heterozygous for the SPT subunit SPTLC2 (serine palmitoyltransferase, long-chain base subunit 2) there is a reduction in peripheral ceramide levels and improved insulin sensitivity when these animals are fed a high-fat diet

After washing the column with the lysis buffer, TEV protease was added into the column for 1 h at room temperature to remove the GHK peptide from the HisTrip beads

[Abstract]2025 Jul 14:S2090-1232(25)00544-2
