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This discovery marked the beginning of decades of research into its potential for cosmetic and medical use

doi: 10.1111/j.1365-2990.2006.00793.x

Electrons from FADH 2 are transferred to ETF, which passes electrons to the ETF-ubiquinone oxidoreductase system (ETF-QO) in the respiratory chain through iron-sulfur clusters, ultimately reducing ubiquinone to ubiquinol

Additionally, the disruption of electron flow in the respiratory chain due to an impaired mitochondrial respiration also leads to a reduced reoxidation of NADH into NAD+, thereby reducing oxidation of pyruvate by the pyruvate dehydrogenase complex
