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Patients with more severe or longstanding deficiency may take longer to notice the full benefit

An experimental model using prenatal treatment of bromodeoxyuridine-rats showed YKS had favorable effects on cerebellar serotonin metabolism, enhancing cognitive ability and reducing locomotor agitation, making it a suitable model for studying ADHD and ASD [161]

While MIC b12 dosages are safe for short-term use, there have been some reports of side effects when used over a long period
