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Novo Nordisk Press Release: Advances early-stage obesity medication, amycretin, to Phase 3 clinical development

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Nat Rev Rheumatol 10 , 561566 (2014)

Kinetic assays showed that rifampicin significantly induced CYP3A4 activity in iHLOs over three days, while ketoconazole consistently suppressed CYP3A4 activity over the same period (Fig