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(2) Metabolic pathway differences: certain microbial metabolites observed in animal models (such as specific indole derivatives) may differ in production levels and metabolic pathways in humans (52)
Oparaugo NC, Ouyang K, Nguyen NPN, Nelson AM, Agak GW
M., Sanchez-Puelles, J
Adipose stem cell exosomal miR-1246 promotes M2 polarization by inhibiting TRAF6, while concurrently targeting FTO and RUNX1T1 to reduce lipogenesis and induce white adipose browning, thereby synergistically ameliorating obesity (300)
