glutathione gst purification pC6-2/caspase-6 system to purify glutathione-S-transferase-free recombinant fusion proteins expressed in Escherichia coli 1 and 3ml with total column volumes of 1 Determination of the GST– glutathione

doi:10.1016/j.freeradbiomed.2017.02.049 73

doi: 10.14336/ad.2014.0500256 8 MartinsSGZilhoRThorsteinsdttirSCarlosAR

Urology 79 , 484.e713 (2012)

Glutathione ng t nht tm vai tr c bn trong cc phn ng chuyn ha v sinh ha bao gm: Tng hp v sa cha DNA Tng hp protein Tng hp prostaglandin (kim sot s co tht hoc gin n ca c trn mch mu v nhiu chc nng sng khc) Vn chuyn axit amin v hot ha enzym Duy tr cc cht chng oxy ha khc nh Vitamin C v E dng hot ng ca chng iu chnh (iu chnh) phn ng min dch thch hp Tng s hin din ca t bo lympho (t bo T, t bo B v t bo st th t nhin) ng thi ci thin hiu qu ca chng iu chnh qu trnh apoptosis (ci cht ca cc t bo xy ra nh mt phn bnh thng v c kim sot ca s tng trng hoc pht trin ca sinh vt.) Do , mi h thng trong c th u c th b nh hng bi mc glutathione, c bit l h thng min dch, h thn kinh, h tiu ha v phi