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Based on the fact that the redox reactive GSHmenadione adducts are excreted, a protective mechanism was proposed to be implicated in catabolic tissues, such as the liver [144,145]

4.2 Antioxidant Considerations Exercise at moderate altitudes is associated with increased production of RONS with reduced antioxidant capacity, leading to oxidative stress [72, 73]

LCLs JY and X50-7 were from the European Collection of Authenticated Cell Cultures (ECACC 94022533) and Cellosaurus (RRID:CVCL_8277), respectively

Simultaneously, it suppresses the production of adhesion molecules dependent on NF-B and the interaction between monocytes and human umbilical vein endothelial cells (HUVECs) (Figure 3) [61]