melanotic macule increased melanocytes Case of in a 46/F Let's review ORAL MELANOTIC MACULE/ FOCAL MELANOSIS . The oral melanotic macule is a flat, brown, mucosal discoloration produced by a focal increase in melanin Melanocytic Proliferations and Other Pigmented

14 Symptoms such as pain, burning, stinging, anaesthesia, paraesthesia, facial paralysis, diplopia and blurred vision are suggestive of neurological involvement

Only free thyroid hormone is metabolically active Thyroid hormone affects metabolism in all tissues in the body via a variety of mechanisms Thyroid hormone increases the expression and sensitivity of beta-adrenergic receptors resulting in an increased response to endogenous catecholamines (this accounts for many of the symptoms seen in thyroid storm) Wolff-Chaikoff Effect: Excess iodide transiently inhibits thyroglobulin iodination and release of thyroid hormone Jod-Basedown Effect: Iodide load induces hyperthyroidism in susceptible subgroups (i.e

Other Ingredients: Lactose, Bulking Agent, Acidity Regulator, Anti-caking Agent, Sweetener, Nature Identical Flavouring Substances and Stabiliser

Classification and Nomenclature of Viruses