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Thyroid hormones increase ROS release in the mitochondrial respiratory chain (82, 83)

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The primary factor contributing to Wilson disease is a mutation in the ATP7B gene, a crucial copper transport protein responsible for biliary copper excretion [122]

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As previously described, the classical proinflammatory categories (i.e., TLR, MAPK, LPS, and IFN signaling) were enriched in the downregulated clusters (12, 35)

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