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Collectively, our findings reveal a crucial role for SIRT7-mediated SRF-K154 deacetylation in limiting AAA progression and suggest that nicotinamide mononucleotide supplementation may represent a promising therapeutic strategy for AAA

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doi: 10.1016/j.jpeds.2012.05.057 76 KalaraniIBVeerabathiranR

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Replicative senescence: an old lives' tale

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This oxidative depletion of BH 4 causes uncoupling of eNOS, where it produces superoxide instead of NO

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