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Despite normal -cell replication, apoptosis is reduced, which ultimately decreases the number of cells by 50% [3]
Likewise, sex differences in the way some of these drugs are absorbed and metabolized has been noted 37 , though we did not observe any differences in L2-Cmu PK or exposure levels between male and female animals
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JAMA Dermatol 152(9):10511052 Balkrishnan R, McMichael AJ, Camacho FT, Saltzberg F, Housman TS, Grummer S et al (2003) Development and validation of a health-related quality of life instrument for women with melasma
