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Further, decreased GSH has been associated with liver disease
However, with physiologic HNE concentrations, induction of GCLC required Nrf2 signaling (Zhang et al., 2007)
A list of principal investigators, affiliated study sites, and information regarding the overseeing IRB is provided in Supplementary Table 1
The active factor was found to be GHK, with human plasma levels around 200 ng/mL at 20 years of age, declining to less than 60 ng/mL at 60 years of age
